Sunitinib US FDA Label
- Compound: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
- Description: Sunitinib is a member of pyrroles and a monocarboxylic acid amide. It has a role as an angiogenesis inhibitor, an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, a vascular endothelial growth factor receptor antagonist, an immunomodulator and a neuroprotective agent. It is functionally related to a 3-methyleneoxindole.
- Brand Name:
- Code(s): SU-11248
- Approved:
- Kinase Class: RY
- Inhibitor Type: IIB, I ½B
- Literature (PubMed): 0
- Target(s): AXL receptor tyrosine kinase , Fms related receptor tyrosine kinase 1 , fms related receptor tyrosine kinase 3 , fms related receptor tyrosine kinase 4 , kinase insert domain receptor , KIT proto-oncogene, receptor tyrosine kinase , Platelet derived growth factor receptor alpha , Platelet derived growth factor receptor beta , RET proto-oncogene
- Disease(s): gastrointestinal stromal tumor , progressive neuroendocrine tumors , renal cell carcinoma